INDEPENDENT PLAYER GUIDEReadable facts. Better choices.
Permanent upgrades

Which Lab upgrades should I prioritise, and which last between runs?

The short answer

The Lab spends Stardust on permanent upgrades for later runs: damage, HP and speed, as well as move and vitamin slots, rerolls, revives, support-team capacity and backpack capacity.

Fix the limit you keep encountering

If builds rarely come together, consider more choices or action uses. If a build needs more moves, inspect the fourth slot; if support or backpack space is the problem, inspect those capacities.

Affinity improves odds, not certainty

Lab affinity makes starred favourite moves appear more often. It changes their weighting, not a guarantee that every upgrade selection will offer one.

Keep exploring